Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

doi:10.1016/j.ajhg.2009.04.006

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Article

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

American journal of human genetics - 1 May 2009

Himes Blanca E, Hunninghake Gary M, Baurley James W, Rafaels Nicholas M, Sleiman Patrick, Strachan David P, Wilk Jemma B, Willis-Owen Saffron A G, Klanderman Barbara, Lasky-Su Jessica, Lazarus Ross, Murphy Amy J, Soto-Quiros Manuel E, Avila Lydiana, Beaty Terri, Mathias Rasika A, Ruczinski Ingo, Barnes Kathleen C, Celedón Juan C, Cookson William O C, Gauderman W James, Gilliland Frank D, Hakonarson Hakon, Lange Christoph, Moffatt Miriam F, O'Connor George T, Raby Benjamin A, Silverman Edwin K, Weiss Scott T

Abstract excerpt

Asthma, a chronic airway disease with known heritability, affects more than 300 million people around the world. A genome-wide association (GWA) study of asthma with 359 cases from the Childhood Asthma Management Program (CAMP) and 846 genetically matched controls from the Illumina ICONdb public resource was performed. The strongest region of association seen was on chromosome 5q12 in PDE4D. The phosphodiesterase...

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Identifiers

PMID: 19426955
DOI: 10.1016/j.ajhg.2009.04.006
PMCID: PMC2681010

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CAMP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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