Article
Genome-wide association studies in the genetics of asthma.
Current allergy and asthma reports - 1 Jan 2009
Willis-Owen Saffron A G, Cookson William O, Moffatt Miriam F
Abstract excerpt
The field of asthma genetics has progressed rapidly over the past decade, implicating many genes and variants in the etiology of this complex disease. However, many of these factors have failed to replicate consistently, indicating a high false-positive rate and/or insufficient power for the detection of small effects. Technological limitations also have restricted the potential to detect novel mechanisms,...
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