Article
Genome-wide association studies (GWAS) and their importance in asthma.
Allergologia et immunopathologia - 1 Jan 2000
García-Sánchez A, Isidoro-García M, García-Solaesa V, Sanz C, Hernández-Hernández L, Padrón-Morales J, Lorente-Toledano F, Dávila I
Abstract excerpt
Asthma is a complex disease determined by the interaction of different genes and environmental factors. The first genetic investigations in asthma were candidate gene association studies and linkage studies. In recent years research has focused on association studies that scan the entire genome without any prior conditioning hypothesis: the so-called genome-wide association studies (GWAS). The first GWAS was...
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