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Article

Polymorphism of the homologous recombination repair genes RAD51 and XRCC3 in breast cancer.

Experimental and molecular pathology - 1 Aug 2009

Krupa Renata, Synowiec Ewelina, Pawlowska Elzbieta, Morawiec Zbigniew, Sobczuk Anna, Zadrozny Marek, Wozniak Katarzyna, Blasiak Janusz

Abstract excerpt

The RAD51 protein and its paralog, XRCC3, play an important role in the repair of DNA double-strand breaks (DSBs) by homologous recombination. Since DSBs may contribute to the pathogenesis of breast cancer and variability in DNA repair genes may be linked with some cancers, we performed a case-control study (135 cases and 175 controls) to check the association between the genotypes of the Thr241Met polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19426727
DOI: 10.1016/j.yexmp.2009.04.005

Genes

XRCC3
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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