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Article

Polymorphisms in RAD51, XRCC2 and XRCC3 genes of the homologous recombination repair in colorectal cancer--a case control study.

Molecular biology reports - 1 Apr 2011

Krupa Renata, Sliwinski Tomasz, Wisniewska-Jarosinska Maria, Chojnacki Jan, Wasylecka Maja, Dziki Lukasz, Morawiec Jan, Blasiak Janusz

Abstract excerpt

XRCC2 and XRCC3 proteins are structurally and functionally related to RAD51 which play an important role in the homologous recombination, the process frequently involved in cancer transformation. In our previous work we show that the 135G>C polymorphism (rs1801320) of the RAD51 gene can modify the effect of the Thr241Met polymorphism (rs861539) of the XRCC3 gene. We tested the association between the 135G>C...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21104022
DOI: 10.1007/s11033-010-0430-6
PMCID: PMC3071932

Genes

RAD51
XRCC3
XRCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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