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Article

RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies.

Breast cancer research and treatment - 1 Feb 2011

Gao Lin-Bo, Pan Xin-Min, Li Li-Juan, Liang Wei-Bo, Zhu Yi, Zhang Lu-Shun, Wei Yong-Gang, Tang Ming, Zhang Lin

Abstract excerpt

Growing evidence suggests that RAD51 plays a pivotal role in the repair of DNA double-strand breaks and the maintenance of genomic stability. A single nucleotide polymorphism, 135G/C, has been identified in the 5' untranslated region of the RAD51 gene and has been shown to influence gene transcription activity. Previous studies yielded conflicting results as to the association of 135G/C polymorphism with breast...

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Identifiers

PMID: 20640595
DOI: 10.1007/s10549-010-0995-8

Genes

RAD51

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies.PMID 20640595Read ↗

RAD51 135G>C polymorphism contributes to breast cancer susceptibility: a meta-analysis involving 26,444 subjects.Semantic proximity Read ↗

RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Association between the RAD51 135 G>C polymorphism and risk of cancer: a meta-analysis of 19,068 cases and 22,630 controls.Semantic proximity Read ↗

RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects.Semantic proximity Read ↗

Genetic 135G/C polymorphism of RAD51 gene and risk of cancer: a meta-analysis of 28,956 cases and 28,372 controls.Semantic proximity Read ↗

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.Semantic proximity Read ↗

RAD51 135G>C does not modify breast cancer risk in non-BRCA1/2 mutation carriers: evidence from a meta-analysis of 12 studies.Semantic proximity Read ↗

RAD51 135G>C substitution increases breast cancer risk in an ethnic-specific manner: a meta-analysis on 21,236 cases and 19,407 controls.Semantic proximity Read ↗

RAD51 Gene 135G/C polymorphism and the risk of four types of common cancers: a meta-analysis.Semantic proximity Read ↗

RAD51 135G>C polymorphism and risk of familial breast cancer in a South American population.Semantic proximity Read ↗

Polymorphic Variants in 5'-UTR Regions of the RAD51 Gene are Associated With RAD51 Expression and Triple-Negative Breast Cancer (TNBC): A Case-Control Study.Semantic proximity Read ↗

135G/C polymorphism in the RAD51 gene and acute myeloid leukemia risk: a meta-analysis.Semantic proximity Read ↗

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