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Article

Expression of Candida glabrata Adhesins after Exposure to Chemical Preservatives

8 May 2009

Abstract excerpt

Adherence of Candida glabrata, an opportunistic yeast pathogen, to host cells is mediated in part by the Epa family of adhesins, which are encoded largely at subtelomeric loci, where they are subject to transcriptional silencing. In analyzing the regulation of the subtelomeric EPA6 gene, we found that its transcription is highly induced after exposure to methylparaben, propylparaben, or sorbate. These weak...

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PMID: 19426114
DOI: 10.1086/599120

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