Article
Telomere length control and transcriptional regulation of subtelomeric adhesins in Candida glabrata.
Molecular microbiology - 1 Feb 2005
Castaño Irene, Pan Shih-Jung, Zupancic Margaret, Hennequin Christophe, Dujon Bernard, Cormack Brendan P
Abstract excerpt
The pathogenic yeast Candida glabrata is able to bind in vitro to human epithelial cells. This interaction depends on expression of the adhesin Epa1p. The genome contains a number of EPA1 paralogues which localize to the subtelomeric regions of the C. glabrata. We have identified three hyperadherent mutants of C. glabrata. The first has an insertion adjacent to EPA7, an EPA1-related adhesin. The others disrupt...
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