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Article

A Protosilencer of Subtelomeric Gene Expression in Candida glabrata with Unique Properties

3 Nov 2011

Abstract excerpt

Adherence to host cells is an important step in the pathogenicity of the opportunistic fungal pathogen Candida glabrata. This adherence is mediated by some members of the large family of cell wall proteins encoded by the EPA (Epithelial Adhesin) genes present in the C. glabrata genome. The majority of the EPA genes are localized close to different telomeres in C. glabrata, resulting in a negative regulation of...

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PMID: 22048024
DOI: 10.1534/genetics.111.135251

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