Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influenza virus recruits host protein kinase C to control assembly and activity of its replication machinery.

eLife - 31 Jul 2017

Mondal Arindam, Dawson Anthony R, Potts Gregory K, Freiberger Elyse C, Baker Steven F, Moser Lindsey A, Bernard Kristen A, Coon Joshua J, Mehle Andrew

Abstract excerpt

Influenza virus expresses transcripts early in infection and transitions towards genome replication at later time points. This process requires de novo assembly of the viral replication machinery, large ribonucleoprotein complexes (RNPs) composed of the viral polymerase, genomic RNA and oligomeric nucleoprotein (NP). Despite the central role of RNPs during infection, the factors dictating where and when they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to A549 Cells
Share to Host-Pathogen Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H1N1 Subtype

Share to Isoenzymes

Share to Madin Darby Canine Kidney Cells

Share to Protein Kinase C-delta

Share to Ribonucleoproteins

Share to RNA-Dependent RNA Polymerase

Source

Open in PubMed Open full text

Identifiers

PMID: 28758638
DOI: 10.7554/eLife.26910
PMCID: PMC5791932

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influenza virus recruits host protein kinase C to control assembly and activity of its replication machinery.PMID 28758638Read ↗

Generation and Comprehensive Analysis of an Influenza Virus Polymerase Cellular Interaction NetworkSemantic proximity Read ↗

Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restrictionSemantic proximity Read ↗

RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase IISemantic proximity Read ↗

Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs.Semantic proximity Read ↗

Role of the PB2 627 Domain in Influenza A Virus Polymerase FunctionSemantic proximity Read ↗

PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.Semantic proximity Read ↗

Influenza virus polymerase: Functions on host range, inhibition of cellular response to infection and pathogenicitySemantic proximity Read ↗

NS5A domain I antagonises PKR to facilitate the assembly of infectious hepatitis C virus particlesSemantic proximity Read ↗

A Conserved Basic Patch and Central Kink in the Nipah Virus Phosphoprotein Multimerization Domain Are Essential for Polymerase FunctionSemantic proximity Read ↗

The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R.Semantic proximity Read ↗

DNA-PK facilitates HIV transcription by regulating the activity of RNA polymerase II and the recruitment of transcription machinery at HIV LTRSemantic proximity Read ↗

Measles Virus C Protein Impairs Production of Defective Copyback Double-Stranded Viral RNA and Activation of Protein Kinase RSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.