Article
Recognition of double strand breaks by a mutator protein (MU2) in Drosophila melanogaster.
PLoS genetics - 1 May 2009
Dronamraju Raghuvar, Mason James M
Abstract excerpt
Telomere capture, a rare event that stabilizes chromosome breaks, is associated with certain genetic abnormalities in humans. Studies pertaining to the generation, maintenance, and biological effects of telomere formation are limited in metazoans. A mutation, mu2(a), in Drosophila melanogaster decreases the rate of repair of double strand DNA breaks in oocytes, thus leading to chromosomes that have lost a natural...
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