Positional identification of variants of Adamts16 linked to inherited hypertension.

doi:10.1093/hmg/ddp218

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Article

Positional identification of variants of Adamts16 linked to inherited hypertension.

Human molecular genetics - 1 Aug 2009

Joe Bina, Saad Yasser, Dhindaw Seema, Lee Norman H, Frank Bryan C, Achinike Ovokeraye H, Luu Truong V, Gopalakrishnan Kathirvel, Toland Edward J, Farms Phyllis, Yerga-Woolwine Shane, Manickavasagam Ezhilarasi, Rapp John P, Garrett Michael R, Coe David, Apte Suneel S, Rankinen Tuomo, Pérusse Louis, Ehret Georg B, Ganesh Santhi K, Cooper Richard S, O'Connor Ashley, Rice Treva, Weder Alan B, Chakravarti Aravinda, Rao Dabeeru C, Bouchard Claude

Abstract excerpt

A previously reported blood pressure (BP) quantitative trait locus on rat Chromosome 1 was isolated in a short congenic segment spanning 804.6 kb. The 804.6 kb region contained only two genes, LOC306664 and LOC306665. LOC306664 is predicted to translate into A Disintegrin-like and Metalloproteinase with Thrombospondin Motifs-16 (Adamts16). LOC306665 is a novel gene. All predicted exons of both LOC306664 and...

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Identifiers

PMID: 19423552
DOI: 10.1093/hmg/ddp218
PMCID: PMC2706685

Genes

ADAMTS16

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