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Article

Common genetic variation in TP53 and risk of human papillomavirus persistence and progression to CIN3/cancer revisited.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2009

Koshiol Jill, Hildesheim Allan, Gonzalez Paula, Bratti M Concepcion, Porras Carolina, Schiffman Mark, Herrero Rolando, Rodriguez Ana C, Wacholder Sholom, Yeager Meredith, Chanock Stephen J, Burk Robert D, Wang Sophia S

Abstract excerpt

Driven by findings that human papillomavirus (HPV)-induced degradation of p53 differs by a TP53 polymorphism at codon 72 (Pro72Arg), past studies of TP53 genetic variants and cervical cancer have focused on this nonsynonymous polymorphism, with mixed results. We analyzed common single nucleotide polymorphisms (SNP) across the TP53 locus in a population-based nested case-control study in Guanacaste, Costa Rica. We...

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Identifiers

PMID: 19423538
DOI: 10.1158/1055-9965.EPI-08-0830
PMCID: PMC2764239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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