Article
TP53 genetic polymorphisms and environmental risk factors associated with cervical carcinogenesis in a cohort of Brazilian women with cervical lesions.
Journal of toxicology and environmental health. Part A - 1 Jan 2010
Ferreira da Silva Ilce, Koifman Rosalina Jorge, Quinto Santos Souza Claudia, Ferreira de Almeida Neto Olimpio, Koifman Sergio
Abstract excerpt
The purpose of this study was to determine the prevalence of TP53 polymorphism at codon 72 and its association with environmental risk factors in a sample of women in Rio de Janeiro, Brazil. A cross-sectional study was conducted with 304 women with histological diagnoses of negative, precancerous, and cancerous lesions between October 2004 and May 2006. Antecedents of exposure to environmental risk factors were...
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