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Article

ERCC1 and XRCC1 gene polymorphisms predict response to neoadjuvant radiochemotherapy in esophageal cancer.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Aug 2009

Warnecke-Eberz Ute, Vallböhmer Daniel, Alakus Hakan, Kütting Fabian, Lurje Georg, Bollschweiler Elfriede, Wienand-Dorweiler Anke, Drebber Uta, Hölscher Arnulf H, Metzger Ralf

Abstract excerpt

INTRODUCTION: Neoadjuvant treatment strategies have been developed to improve survival of patients with locally advanced esophageal cancer. Since only patients with major histopathological response benefit from this therapy, predictive markers are needed. We examined a panel of selected gene polymorphisms to predict response to neoadjuvant radiochemotherapy (cisplatin, 5-fluorouracil, 36 Gy) in esophageal cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19421825
DOI: 10.1007/s11605-009-0881-z

Genes

ERCC1
XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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