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Article

ERCC1 C8092A (rs3212986) polymorphism as a predictive marker in esophageal cancer patients treated with cisplatin/5-FU-based neoadjuvant therapy.

Pharmacogenetics and genomics - 1 Nov 2013

Rumiato Enrica, Cavallin Francesco, Boldrin Elisa, Cagol Matteo, Alfieri Rita, Basso Daniela, Castoro Carlo, Ancona Ermanno, Amadori Alberto, Ruol Alberto, Saggioro Daniela

Abstract excerpt

OBJECTIVE: At present, no consensus exists on the beneficial effect of preoperative cisplatin/5-fluorouracil (5-FU)-based chemotherapy versus primary surgery in the management of patients with esophageal cancer. The aim of this study was to evaluate the impact of some relevant genetic polymorphisms, within drug-related and DNA repair genes, on the clinical outcome of esophageal cancer patients subjected to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23962907
DOI: 10.1097/FPC.0b013e3283653afc

Genes

ERCC1
ERCC2
GSTM1
GSTP1
GSTT1

Variants

rs3212986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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