Article
Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan.
PloS one - 1 Jan 2009
Yang Hsin-Chou, Liang Yu-Jen, Wu Yi-Lin, Chung Chia-Min, Chiang Kuang-Mao, Ho Hung-Yun, Ting Chih-Tai, Lin Tsung-Hsien, Sheu Sheng-Hsiung, Tsai Wei-Chuan, Chen Jyh-Hong, Leu Hsin-Bang, Yin Wei-Hsian, Chiu Ting-Yu, Chen Chin-Iuan, Fann Cathy S J, Wu Jer-Yuarn, Lin Teng-Nan, Lin Shing-Jong, Chen Yuan-Tsong, Chen Jaw-Wen, Pan Wen-Harn
Abstract excerpt
Young-onset hypertension has a stronger genetic component than late-onset counterpart; thus, the identification of genes related to its susceptibility is a critical issue for the prevention and management of this disease. We carried out a two-stage association scan to map young-onset hypertension susceptibility genes. The first-stage analysis, a genome-wide association study, analyzed 175 matched case-control...
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