Article
Molecular diversity of SIVsmm/PBj and a cognate variant, SIVsmm/PGg.
Journal of medical primatology - 1 Jun 1991
Novembre F J, Hirsch V M, McClure H M, Johnson P R
Abstract excerpt
The molecular diversity of SIVsmm/PBj proviral genomes in tissues of an infected macaque was analyzed. Molecular clones derived directly from intestinal tissue DNA were heterogenous, and contained LTRs with one or two NF-kB binding sites. LTRs with one NF-kB site predominated (approximately 75%). Virions derived from biologically active chimeric DNA clones with one or two NF-kB sites did not induce the acute...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Cloning, Molecular
- DNA, Viral
- Genetic Variation
- HIV Enhancer
- HIV Envelope Protein gp120
- Humans
- Macaca nemestrina
- Membrane Glycoproteins
