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Article

Human immunodeficiency virus type 1 nef quasispecies in pathological tissue.

Journal of virology - 1 Sept 1992

Blumberg B M, Epstein L G, Saito Y, Chen D, Sharer L R, Anand R

Abstract excerpt

The role of the nef gene in human immunodeficiency virus type 1 (HIV-1) infection is poorly understood. To provide a basis for studies on the role of nef in AIDS, we used targeted polymerase chain reaction amplification and DNA sequencing to determine the structure of nef genes in pathologic tissue from HIV-1-infected children and adults. We find that the nef reading frame is open in 92% of clones derived from...

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Identifiers

PMID: 1501274
DOI: 10.1128/JVI.66.9.5256-5264.1992
PMCID: PMC289079

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Human immunodeficiency virus type 1 nef quasispecies in pathological tissue.PMID 1501274Read ↗

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