Article
Human immunodeficiency virus type 1 nef quasispecies in pathological tissue.
Journal of virology - 1 Sept 1992
Blumberg B M, Epstein L G, Saito Y, Chen D, Sharer L R, Anand R
Abstract excerpt
The role of the nef gene in human immunodeficiency virus type 1 (HIV-1) infection is poorly understood. To provide a basis for studies on the role of nef in AIDS, we used targeted polymerase chain reaction amplification and DNA sequencing to determine the structure of nef genes in pathologic tiss...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- Amino Acid Sequence
- Base Sequence
- Brain
- Cerebrospinal Fluid
- Child
- Child, Preschool
- Democratic Republic of the Congo
- Genes, nef
- Genetic Variation
- HIV-1
- Humans
- Lymphocytes
- Molecular Sequence Data
- Multigene Family
- Mutagenesis
- New Jersey