Article
The dyslexia-associated protein KIAA0319 interacts with adaptor protein 2 and follows the classical clathrin-mediated endocytosis pathway.
American journal of physiology. Cell physiology - 1 Jul 2009
Levecque Clotilde, Velayos-Baeza Antonio, Holloway Zoe G, Monaco Anthony P
Abstract excerpt
Recently, genetic studies have implicated KIAA0319 in developmental dyslexia, the most common of the childhood learning disorders. The first functional data indicated that the KIAA0319 protein is expressed on the plasma membrane and may be involved in neuronal migration. Further analysis of the subcellular distribution of the overexpressed protein in mammalian cells indicates that KIAA0319 can colocalize with the...
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