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Article

Roles of developmentally regulated KIF2A alternative isoforms in cortical neuron migration and differentiation.

Development (Cambridge, England) - 22 Feb 2021

Akkaya Cansu, Atak Dila, Kamacioglu Altug, Akarlar Busra Aytul, Guner Gokhan, Bayam Efil, Taskin Ali Cihan, Ozlu Nurhan, Ince-Dunn Gulayse

Abstract excerpt

KIF2A is a kinesin motor protein with essential roles in neural progenitor division and axonal pruning during brain development. However, how different KIF2A alternative isoforms function during development of the cerebral cortex is not known. Here, we focus on three Kif2a isoforms expressed in the developing cortex. We show that Kif2a is essential for dendritic arborization in mice and that the functions of all...

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PMID: 33531432
DOI: 10.1242/dev.192674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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