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Article

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.

PLoS genetics - 1 Mar 2009

Dennis Megan Y, Paracchini Silvia, Scerri Thomas S, Prokunina-Olsson Ludmila, Knight Julian C, Wade-Martins Richard, Coggill Penny, Beck Stephan, Green Eric D, Monaco Anthony P

Abstract excerpt

Numerous genetic association studies have implicated the KIAA0319 gene on human chromosome 6p22 in dyslexia susceptibility. The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has been implicated in the reduced expression of KIAA0319, and (2) the strongest association has been found for the region spanning exon 1 of KIAA0319. Here, we test the...

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Identifiers

PMID: 19325871
DOI: 10.1371/journal.pgen.1000436
PMCID: PMC2653637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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