Article
Polymorphisms in TCEAL7 and risk of epithelial ovarian cancer.
Gynecologic oncology - 1 Aug 2009
Peedicayil Abraham, Vierkant Robert A, Shridhar Vijayalakshmi, Schildkraut Joellen M, Armasu Sebastian, Hartmann Lynn C, Fridley Brooke L, Cunningham Julie M, Phelan Catherine M, Sellers Thomas A, Goode Ellen L
Abstract excerpt
OBJECTIVE: We have previously shown that TCEAL7 (transcription elongation factor A (SII)-like 7) is epigenetically down-regulated in the majority of epithelial ovarian cancers. We now examine the hypothesis that inherited alterations in TCEAL7 play a role in the etiology of ovarian cancer. METHODS: A two-site case-control study of 930 cases of ovarian cancer and 1037 controls, frequency-matched on residence, age...
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