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Gene variants of TCF7L2 are histopathologically important in colorectal cancers but do not have direct association with MYC expression.

Cellular and molecular biology (Noisy-le-Grand, France) - 31 Dec 2019

Ozkan Kucuk Nazlı Ezgi, Horozoglu Cem, Timirci Kahraman Ozlem, Arikan Soykan, Farooqi Ammad Ahmad, Turan Saime, Korkmaz Gurbet, Kelten Talu Esra Canan, Sabitaliyevich Uteuliyev Yerzhan, Yaylim Ilhan

Abstract excerpt

Rapidly accumulating preclinical and clinical studies have helped us to unveil underlying mechanisms of colorectal cancer development and progression. Deregulated signaling pathways play instrumental role in carcinogenesis, drug resistance and metastasis. Wnt signaling cascade has attracted considerable attention in colorectal cancer as many ground-breaking researches have highlighted central role of Wnt pathway...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32133972

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