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Article

Utilizing linkage disequilibrium information from Indian Genome Variation Database for mapping mutations: SCA12 case study.

Journal of genetics - 1 Apr 2009

Bahl Samira, Ahmed Ikhlak, Mukerji Mitali

Abstract excerpt

Stratification in heterogeneous populations poses an enormous challenge in linkage disequilibrium (LD) based identification of causal loci using surrogate markers. In this study, we demonstrate the enormous potential of endogamous Indian populations for mapping mutations in candidate genes using minimal SNPs, mainly due to larger regions of LD. We show this by a case study of the PPP2R2B gene (approximately 400...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19417544
DOI: 10.1007/s12041-009-0007-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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