Article
Clinical significance of chromosomal integrity in gastric cancers.
The International journal of biological markers - 1 Sept 2022
Zhang Rukui, Liu Zhaorui, Chang Xusheng, Gao Yuan, Han Huan, Liu Xiaona, Cai Hui, Fu Qiqing, Liu Lei, Yin Kai
Abstract excerpt
BACKGROUND: A whole-exome or targeted cancer genes panel by next-generation sequencing has been used widely in assisting individualized treatment decisions. Currently, multiple algorithms are developed to estimate DNA copy numbers based on sequencing data, which makes a comprehensive global glance at chromosomal integrity possible. We aim to classify gastric cancers based on chromosomal integrity to guide...
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