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Widespread reductions of cortical thickness in schizophrenia and spectrum disorders and evidence of heritability.

Archives of general psychiatry - 1 May 2009

Goldman Aaron L, Pezawas Lukas, Mattay Venkata S, Fischl Bruce, Verchinski Beth A, Chen Qiang, Weinberger Daniel R, Meyer-Lindenberg Andreas

Abstract excerpt

CONTEXT: Schizophrenia is a brain disorder with predominantly genetic risk factors, and previous research has identified heritable cortical and subcortical reductions in local brain volume. To our knowledge, cortical thickness, a measure of particular interest in schizophrenia, has not previously been evaluated in terms of its heritability in relationship to risk for schizophrenia. OBJECTIVE: To quantify the...

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Identifiers

PMID: 19414706
DOI: 10.1001/archgenpsychiatry.2009.24
PMCID: PMC2719488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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