Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription.

Circulation research - 29 Aug 2008

Rouf Rosanne, Greytak Sarah, Wooten Eric C, Wu Jing, Boltax Jay, Picard Michael, Svensson Eric C, Dillmann Wolfgang H, Patten Richard D, Huggins Gordon S

Abstract excerpt

Reduced expression of sarcoplasmic reticulum calcium ATPase (SERCA)2 and other genes in the adult cardiac gene program has raised consideration of an impaired responsiveness to thyroid hormone (T3) that develops in the advanced failing heart. Here, we show that human and murine cardiomyopathy hea...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathies
Share to Echocardiography
Share to Heart Failure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred ICR

Share to Myocytes, Cardiac

Share to Sarcoplasmic Reticulum Calcium-Transporting ATPases

Share to Thyroid Hormone Receptors alpha

Share to Triiodothyronine

Source

Open in PubMed Open full text

Identifiers

PMID: 18658259
DOI: 10.1161/CIRCRESAHA.108.181487
PMCID: PMC2650841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18658259-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription.PMID 18658259Read ↗

Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.Semantic proximity Read ↗

A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory NetworkSemantic proximity Read ↗

FOG-2, a Cofactor for GATA Transcription Factors, Is Essential for Heart Morphogenesis and Development of Coronary Vessels from EpicardiumSemantic proximity Read ↗

FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development.Semantic proximity Read ↗

Fog1 is required for cardiac looping in zebrafish.Semantic proximity Read ↗

Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter.Semantic proximity Read ↗

Translational Control of FOG-2 Expression in Cardiomyocytes by MicroRNA-130aSemantic proximity Read ↗

Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.Semantic proximity Read ↗

The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors.Semantic proximity Read ↗

Combinatorial cis-Acting Elements Control Tissue-specific Activation of the Cardiac Troponin I Gene in Vitro and in VivoSemantic proximity Read ↗

Transcriptional Genomics Associates FOX Transcription Factors With Human Heart FailureSemantic proximity Read ↗

Cardiac troponin T is essential in sarcomere assembly and cardiac contractility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.