Article
Immunogenetic risks of anti-cyclical citrullinated peptide antibodies in a North American Native population with rheumatoid arthritis and their first-degree relatives.
The Journal of rheumatology - 1 Jun 2009
El-Gabalawy Hani S, Robinson David B, Hart Donna, Elias Brenda, Markland Janet, Peschken Christine A, Smolik Irene, Montes-Aldana Gabriela, Schroeder Marlis, Fritzler Marvin J, Cheang Mary, Oen Kiem
Abstract excerpt
OBJECTIVE: To determine the prevalence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in unaffected relatives of North American Native probands with rheumatoid arthritis (RA); and the associations of the shared epitope (SE) and HLA-DRB1*0901 with RA and anti-CCP antibodies. METHODS: The subjects were RA probands, affected relatives, unaffected first-degree (FDR) and more distant relatives, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.