Article
Detection of early behavioral markers of Huntington's disease in R6/2 mice employing an automated social home cage.
Behavioural brain research - 5 Nov 2009
Rudenko Olga, Tkach Vadim, Berezin Vladimir, Bock Elisabeth
Abstract excerpt
Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder, for which no known cure or effective treatment exists. To facilitate the search for new potential treatments of HD, an automated system for analyzing the behavior of transgenic HD mice is urgently needed. A recently developed behavior screening system, the IntelliCage, allows automated testing of mouse behavior in the home cage...
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