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Article

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.

Neurobiology of disease - 1 Sept 2009

Menalled Liliana, El-Khodor Bassem F, Patry Monica, Suárez-Fariñas Mayte, Orenstein Samantha J, Zahasky Benjamin, Leahy Christina, Wheeler Vanessa, Yang X William, MacDonald Marcy, Morton A Jennifer, Bates Gill, Leeds Janet, Park Larry, Howland David, Signer Ethan, Tobin Allan, Brunner Daniela

Abstract excerpt

Huntington's disease (HD) is one of the few neurodegenerative diseases with a known genetic cause, knowledge that has enabled the creation of animal models using genetic manipulations that aim to recapitulate HD pathology. The study of behavioral and neuropathological phenotypes of these HD models, however, has been plagued by inconsistent results across laboratories stemming from the lack of standardized...

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Identifiers

PMID: 19464370
DOI: 10.1016/j.nbd.2009.05.007
PMCID: PMC2728344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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