Article
XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors.
Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2009
Schlaberg Robert, Choe Daniel J, Brown Kristy R, Thaker Harshwardhan M, Singh Ila R
Abstract excerpt
Xenotropic murine leukemia virus-related virus (XMRV) was recently discovered in human prostate cancers and is the first gammaretrovirus known to infect humans. While gammaretroviruses have well-characterized oncogenic effects in animals, they have not been shown to cause human cancers. We provide experimental evidence that XMRV is indeed a gammaretrovirus with protein composition and particle ultrastructure...
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