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Article

Mechanical control of global cell behaviour during dorsal closure in Drosophila.

Development (Cambridge, England) - 1 Jun 2009

Gorfinkiel Nicole, Blanchard Guy B, Adams Richard J, Martinez Arias Alfonso

Abstract excerpt

Halfway through embryonic development, the epidermis of Drosophila exhibits a gap at the dorsal side covered by an extraembryonic epithelium, the amnioserosa (AS). Dorsal closure (DC) is the process whereby interactions between the two epithelia establish epidermal continuity. Although genetic and biomechanical analysis have identified the AS as a force-generating tissue, we do not know how individual cell...

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Identifiers

PMID: 19403661
DOI: 10.1242/dev.030866
PMCID: PMC2680111

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Source receipt: pubmed, retrieved 7 Sept 2026.

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