Article
A biomechanical analysis of ventral furrow formation in the Drosophila melanogaster embryo.
PloS one - 1 Jan 2012
Conte Vito, Ulrich Florian, Baum Buzz, Muñoz Jose, Veldhuis Jim, Brodland Wayne, Miodownik Mark
Abstract excerpt
The article provides a biomechanical analysis of ventral furrow formation in the Drosophila melanogaster embryo. Ventral furrow formation is the first large-scale morphogenetic movement in the fly embryo. It involves deformation of a uniform cellular monolayer formed following cellularisation, and has therefore long been used as a simple system in which to explore the role of mechanics in force generation. Here...
Topics
- Animals
- Biomechanical Phenomena
- Drosophila melanogaster
- Embryo, Nonmammalian
- Embryonic Development
- Genotype
- Models, Biological