Article
Wound healing recapitulates morphogenesis in Drosophila embryos.
Nature cell biology - 1 Nov 2002
Wood William, Jacinto Antonio, Grose Richard, Woolner Sarah, Gale Jonathan, Wilson Clive, Martin Paul
Abstract excerpt
The capacity to repair a wound is a fundamental survival mechanism that is activated at any site of damage throughout embryonic and adult life. To study the cell biology and genetics of this process, we have developed a wounding model in Drosophila melanogaster embryos that allows live imaging of rearrangements and changes in cell shape, and of the cytoskeletal machinery that draws closed an in vivo wound. Using...
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