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Article

Low dose radiation-induced adaptive response preventing HPRT mutation is Fhit independent.

International journal of radiation biology - 1 Jun 2009

Lu Lin, Hu Baocheng, Yu Fang, Wang Ya

Abstract excerpt

PURPOSE: To study whether fragile histidine triad (Fhit) prevents IR-induced hypoxanthineguanine phosphoribosyltransferase (HPRT) mutation and whether Fhit plays any role in preventing HPRT mutation through low dose-induced adaptive response. MATERIALS AND METHODS: Establishing human cell lines with or without Fhit expression by making constructs expressing hemagglutinin (HA) alone or HA-Fhit fusion protein and...

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Identifiers

PMID: 19401904
DOI: 10.1080/09553000902883828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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