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Article

Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis.

Breast cancer research : BCR - 1 Jan 2009

Reed Johanna R, Leon Ronald P, Hall Majken K, Schwertfeger Kathryn L

Abstract excerpt

INTRODUCTION: Inflammation within the tumour microenvironment correlates with increased invasiveness and poor prognosis in many types of cancer, including breast cancer. We have previously demonstrated that activation of a mouse mammary tumour virus (MMTV)-driven inducible fibroblast growth factor receptor 1 (iFGFR1) transgene in mammary epithelial cells results in an inflammatory response characterised by...

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Share to Cyclooxygenase 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mammary Neoplasms, Experimental

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Share to Receptor, Fibroblast Growth Factor, Type 1

Source

Open in PubMed Open full text

Identifiers

PMID: 19393083
DOI: 10.1186/bcr2246
PMCID: PMC2688950

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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