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Article

Haplotype analysis of the NADPH oxidase p22 phox gene in patients with bronchial asthma.

International archives of allergy and immunology - 1 Jan 2009

Izakovicova Holla Lydie, Kanková Katerina, Znojil Vladimir

Abstract excerpt

BACKGROUND: Superoxide produced by airway epithelial and inflammatory cells may contribute to the pathogenesis of asthma. NADPH oxidase (an enzyme complex made up of 5 subunits) is a major source of superoxide in cells. We sought to elucidate the role of genetic variability in the gene encoding the p22(phox) subunit of the NADPH oxidase (CYBA, 16q24.3) in asthma susceptibility by means of an association study of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18716406
DOI: 10.1159/000151508

Genes

CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Haplotype analysis of the NADPH oxidase p22 phox gene in patients with bronchial asthma.PMID 18716406Read ↗

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CYBA (p22phox) variants associate with blood pressure and oxidative stress markers in hypertension: a replication study in populations of diverse altitudes.Semantic proximity Read ↗

C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils.Semantic proximity Read ↗

The C242T CYBA polymorphism as a major determinant of NADPH oxidase activity in patients with cardiovascular disease.Semantic proximity Read ↗

The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension.Semantic proximity Read ↗

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Is the C242T Polymorphism of the CYBA Gene Linked with Oxidative Stress-Associated Complications of Prematurity?Semantic proximity Read ↗

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