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Article

Heterozygote Advantage of the rs3794624 Polymorphism in CYBA for Resistance to Tuberculosis in Two Chinese Populations.

Scientific reports - 30 Nov 2016

Liu Qianqian, Wu Shouquan, Xue Miao, Sandford Andrew J, Wu Jingcan, Wang Yu, Chen Guo, Tao Chuanmin, Tang Yin, Feng Yulin, Luo Jun, He Jian-Qing

Abstract excerpt

Phagocyte Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase complex is a key enzyme that catalyzes the production of reactive oxygen species, which mediate oxygen-dependent killing of microorganisms, such as Mycobacterium tuberculosis. P22phox, encoded by CYBA, is the key regulatory subunit of NADPH oxidase. Our study aimed to investigate the association of CYBA polymorphisms with susceptibility to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27901128
DOI: 10.1038/srep38213
PMCID: PMC5128811

Genes

CYBA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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