Article
Effect of the CYBA C242T Polymorphism on Preeclampsia Pathogenesis in the Chinese Population.
Biochemical genetics - 1 Jun 2024
Zhang Ru, Liu Shuhui, Tan Ping, Guo Zihan, Hou Huabin, Liu Shiguo, Li Hui, Wang Xibing
Abstract excerpt
BACKGROUND: Although the mechanisms responsible for the pathogenesis of preeclampsia (PE) have not been entirely clarified, oxidative stress is thought to be its leading cause. As a major component responsible for reactive oxygen species (ROS) production during oxidative stress, p22phox, encoded by CYBA, is an essential subunit of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. The aim of this study...
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