Article
The role of CYBA (p22phox) and catalase genetic polymorphisms and their possible epistatic interaction in cervical cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015
Castaldo Stephanie Anais, da Silva Alda Pereira, Matos Andreia, Inácio Ângela, Bicho Manuel, Medeiros Rui, Alho Irina, Bicho Maria Clara
Abstract excerpt
Human papillomavirus (HPV) infection is necessary but not a sufficient cause for the development of invasive cervical cancer (ICC). Epithelial tissues, target for HPV, are exposed to reactive oxygen species (ROS) associated with tumor initiation and progression. The NADPH oxidase (NOX) and catala...
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