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Article

The heritability and genetics of complement C3 expression in UK SLE families.

Genes and immunity - 1 Jul 2009

Rhodes B, Hunnangkul S, Morris D L, Hsaio L-C, Graham D S Cunninghame, Nitsch D, Whittaker J C, Vyse T J

Abstract excerpt

As the central component of the complement system, C3 has sensory and effector functions bridging innate and adaptive immunity. It is plausible that common genetic variation at C3 determines either serum C3 level or susceptibility to systemic lupus erythematosus (SLE), but only a single, Japanese, study has currently showed genetic association. In a cohort of 1371 individuals from 393 UK white European SLE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19387462
DOI: 10.1038/gene.2009.23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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