Article
Complement component 3 haplotypes influence serum complement activity and milk production traits in Chinese Holstein cattle.
PloS one - 1 Jan 2022
Wang Yonghui, Zhai Junyu, Yang Chunhong, Wang Jingpeng, Sun Yan, Li Yuhua, Ju Zhihua, Huang Jingming, Wang Changfa
Abstract excerpt
Complement component 3 (C3) is the key molecule of the three pathways of complement activation (alternative, classical, and lectin pathways), which are involved in phagocytosis, inflammation, and immunoregulation processes to destroy infectious microorganisms. In this study, three novel single-nucleotide polymorphisms (SNPs) (g.-1293C>G located in the 5'-flanking region, g.56T>C in exon I, and g.7017C>T in exon...
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