Article
Purified Mesenchymal Stem Cells Are an Efficient Source for iPS Cell Induction
11 Mar 2011
Abstract excerpt
BACKGROUND: Induced pluripotent stem (iPS) cells are generated from mouse and human somatic cells by the forced expression of defined transcription factors. Although most somatic cells are capable of acquiring pluripotency with minimal gene transduction, the poor efficiency of cell reprogramming and the uneven quality of iPS cells are still important problems. In particular, the choice of cell type most suitable...
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