Article
MIR-34c regulates mouse embryonic stem cells differentiation into male germ-like cells through RARg.
Cell biochemistry and function - 1 Dec 2012
Zhang Shanshan, Yu Meng, Liu Chao, Wang Long, Hu Yue, Bai Yaofu, Hua Jinlian
Abstract excerpt
Embryonic stem cells (ESCs) have the capacity to differentiate into nearly all sorts of cell types, including germ cells, which were regarded as one type of highly specialized cells in mammals, taking the responsibility of transferring genetic materials to the next generation. Studies on induction differentiation of murine embryonic stem cells (mESCs) into male germ cells, but with a low efficiency, basic reason...
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