Article
Mouse embryonic fibroblasts (MEF) exhibit a similar but not identical phenotype to bone marrow stromal stem cells (BMSC).
Stem cell reviews and reports - 1 Jun 2012
Saeed Hamid, Taipaleenmäki Hanna, Aldahmash Abdullah M, Abdallah Basem M, Kassem Moustapha
Abstract excerpt
Mouse embryonic fibroblasts have been utilized as a surrogate stem cell model for the postnatal bone marrow-derived stromal stem cells (BMSC) to study mesoderm-type cell differentiation e.g. osteoblasts, adipocytes and chondrocytes. However, no formal characterization of MEF phenotype has been reported. Utilizing standard in vitro and in vivo assays we performed a side-by-side comparison of MEF and BMSC to...
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