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Article

Species-specific in vivo engraftment of the human BL melanoma cell line results in an invasive dedifferentiated phenotype not present in xenografts.

Cancer research - 1 May 2009

Cedervall Jessica, Jamil Seema, Prasmickaite Lina, Cheng YenFu, Eskandarpour Malihe, Hansson Johan, Maelandsmo Gunhild M, Ringborg Ulrik, Gulyas Miklos, Zhen He Suo, Kanter Lena, Ahrlund-Richter Lars

Abstract excerpt

For clinically relevant studies on melanoma progression and invasiveness, in vivo experimental systems with a human cellular microenvironment would be advantageous. We have compared tumor formation from a human cutaneous malignant melanoma cell line (BL), after injection as conventional xenografts in the mouse, or when injected into a predominantly species-specific environment of human embryonic stem cell-derived...

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PMID: 19383913
DOI: 10.1158/0008-5472.CAN-08-3746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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