Article
Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment.
Proceedings of the National Academy of Sciences of the United States of America - 7 Mar 2006
Kulesa Paul M, Kasemeier-Kulesa Jennifer C, Teddy Jessica M, Margaryan Naira V, Seftor Elisabeth A, Seftor Richard E B, Hendrix Mary J C
Abstract excerpt
Human metastatic melanoma cells express a dedifferentiated, plastic phenotype, which may serve as a selective advantage, because melanoma cells invade various microenvironments. Over the last three decades, there has been an increased focus on the role of the tumor microenvironment in cancer prog...
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