Article
Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 May 2009
Dickinson J L, Perera D I, van der Mei A F, Ponsonby A-L, Polanowski A M, Thomson R J, Taylor B V, McKay J D, Stankovich J, Dwyer T
Abstract excerpt
Multiple studies have provided evidence for an association between reduced sun exposure and increased risk of multiple sclerosis (MS), an association likely to be mediated, at least in part, by the vitamin D hormonal pathway. Herein, we examine whether the vitamin D receptor (VDR), an integral component of this pathway, influences MS risk in a population-based sample where winter sun exposure in early childhood...
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