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Article

Multiple sclerosis, vitamin D, and HLA-DRB1*15.

Neurology - 8 Jun 2010

Handunnetthi Lahiru, Ramagopalan Sreeram V, Ebers George C

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) has a remarkable geographic distribution inversely paralleling that of regional ultraviolet radiation, supporting the hypothesis that vitamin D plays a central role in the disease etiology. The major histocompatibility complex exerts the largest genetic contribution to MS susceptibility, but much risk remains unexplained and direct gene-environment interaction is a strong...

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Identifiers

PMID: 20530326
DOI: 10.1212/WNL.0b013e3181e24124
PMCID: PMC2882222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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